Oligo lactic acid®︎

What is Oligo Lactic Acid ®︎

肌の潤い、便通改善、コエンザイムQ10増加、血流改善、脂質代謝改善、乳酸菌増殖作用、免疫力向上、肝機能改善(Moisturizes the skin, improves bowel movements, increases coenzyme Q10, improves blood flow, improves lipid metabolism, proliferates lactic acid bacteria, improves immunity, and improves liver function.)

Oligolactic acid is produced by fermentation and purification of natural sugars with lactic acid bacteria that produce only L-lactic acid, the same lactic acid found in the human body. The resulting L-lactic acid is an original raw material made by dehydration and condensation of lactic acid using our patented proprietary technology.

複数の乳酸分子が一列につながった構造 (オリゴマー)(Structure in which multiple lactic acid molecules are connected in a line (oligomer)) 工場の機械

It is shaped like multiple lactic acid molecules connected in a row, and the linear chain of lactic acid molecules exhibits a variety of functional properties. Oligo Lactic Acid ®︎ is made from lactic acid, a biological substance found in the human body, making it a safe and very healthy food ingredient. In the past, lactic acid was sometimes called a fatigue substance, but it is now known that it is not a cause of fatigue, but rather an important source of energy for the brain and heart.

Benefits of Oligo Lactic Acid ®︎

Oligo lactic acid to meet the needs of the future: ®︎

As dietary supplements become more diversified, there is a demand for higher quality and added value in addition to the characteristics and functionality of raw materials. Oligo Lactic Acid ®︎ has been actively collecting evidence data for some time in order to meet such needs, and has accumulated evidence on function and safety through in vitro and in vivo studies as well as clinical studies. Currently, we are also working on obtaining Food with Functional Labeling. We have a lot of achievements. "Oligolactic acid [LAC]."is a high potential, domestically manufactured raw material.

机の真ん中にノートパソコンがあり、デスクで打合せをしている4人の男女

Confirmed Effects

  • Improvement of skin's water retention function
  • Intestinal regulating effects such as improved bowel movements
  • Improved blood flow
  • mitochondrial activation
  • Lactic acid bacteria growth effect
  • Effect on macrophage migration
  • NK activity enhancing ability
  • Improved liver function
  • Hyperlipidemia improvement effect

Safety and toxicity studies conducted

  • acute toxicity test
  • 90-day repeated-dose study
  • reverse mutation test

Evidence from Oligo Lactic Acid ®︎

Confirmed Effects

  • Title:Effects of Oligolactic Acid (LAC) Intake on Bowel Movements, Intestinal Function and Skin Quality - A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study
  • Subject:A total of 27 Japanese women aged 20~60 years old with constipation and normal, dry skin (13 subjects (oligolactic acid 200mg/day) and 14 subjects (placebo))
  • Your Bibliography:Pharmacology and Therapeutics vol.51 No.1 2023
  • Contents:Oligolactic acid 200 mg/day for 4 weeks showed significant improvement in transdermal water evaporation, an indicator of skin barrier function, significant decrease in average pore area, and bowel regulation effects such as improved bowel movements.

Improved skin barrier function (reduced transdermal water evaporation)

経皮水分蒸散量 (g/h㎡)(Transepidermal water transpiration (g/h㎡))

Improved bowel movements (increased frequency of defecation)

排便回数 (回/2週)(Defecation frequency (times/2 weeks))

Histogram of oligolactate ®︎ before and after intake (Confirmation of the tendency of constipation improvement in quantification of 8 items of LT (CAS-LT))

日本語版評価尺度LT(CAS-LT)の8項目を数値化した便秘評価尺度の摂取前後のヒストグラム(Histogram before and after intake of the constipation evaluation scale that quantifies the 8 items of the Japanese version of the evaluation scale LT (CAS-LT))

Mitochondrial activation action of oligolactate ®︎

Confirmed Effects

  • Title:Oligolactate Enhances Mitochondrial Function and Improves Lipid Metabolism in Mature Japanese Men with Visceral Fat Obesity (MS) Prevalence - A Double-Blind Comparative Study
  • Subject:Total 20 elderly Japanese males aged 55-65 years with BMI between 23 and 30 (10 in the test food group (oligolactic acid 300 mg/day), 10 in the target group)
  • Your Bibliography:Functional Foods and Pharmacognosy Nutrition vol.9 No.4 December 2015
  • Contents:Oligolactate 300mg/day for 1~3 months increased coenzyme Q10 (ubiquinone, ubiquinol) in the body, significantly increased HDL-c, which is called good cholesterol, and significantly suppressed AI index.

Increase of coenzyme Q10 in the body, improvement of lipid metabolism (Confirmation of constipation improvement trend in LT (CAS-LT) quantification of 8 items)

血中コエンザイムQ10(ユビキノン、ユビキノール)のTotal量の変化(Changes in the total amount of coenzyme Q10 (ubiquinone, ubiquinol) in the blood)

Oligolactic acid ®︎ improves blood flow

Confirmed Effects

  • Title:Oligolactic acid intake improves blood flow - A double-blind, parallel-group study
  • Subject:Total 15 healthy male and female subjects aged 20-60 years (8 subjects in the test food group (oligolactic acid 300 mg/day), 7 subjects in the target group)
  • Your Bibliography:unpublished
  • Contents:Increased blood flow in the hand and foot endings was observed after 300 mg/day of oligolactic acid for 3 weeks.

Increased blood flow

                   LAC非摂取 / 摂取 |血流量 (最大時) の対control比(LAC non-intake/intake | Blood flow (maximum) vs. control ratio)

Contract development using raw materials from Oligo Lactic Acid ®︎! (OEM/ODM for GRAIN)

We will develop on consignment with our original raw material "Oligo Lactic Acid ®︎"!

We offer contract development with our original raw material "Oligolactic acid ®︎"! Based on the deep understanding of raw materials cultivated through the development of oligolactic acid, GRAIN Corporation offers optimal product design to our clients. We can offer one-stop service for a wide range of supplements and cosmetics for human use.


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